Exercise as medicine.
Your evidence-based movement guide — every exercise matched to the research that supports it.
Resistance training reduces disease activity. Pilates reduces pain. Tai Chi quiets the stress-inflammation axis. Aerobic training protects your heart. Exercise snacks keep all three pathways active throughout the day. This page teaches you how to do each one safely.
The evidence. A meta-analysis of 17 RCTs (Ye 2021, Medicine) found resistance training reduced RA disease activity (DAS28) by SMD −0.69 — the strongest effect of any exercise modality. The included trials ranged from 30% to 100% of 1-rep max. Your contracting muscles produce exercise IL-6, which stimulates your body's own version of anakinra (IL-1ra) — a built-in anti-inflammatory response.
Bodyweight squat
Reverse lunge
Hip hinge (deadlift pattern)
Wall push-up → floor push-up
Overhead press (bodyweight)
Adding load · 60–70% of your 1-rep max. This matches the intensity used in the majority of the 17 RCTs in the Ye 2021 meta-analysis — including Häkkinen 2001 (50–70% 1RM, 2x/week, 104 weeks) and van den Ende 2000 (60% 1RM). The ACSM classifies 60–70% 1RM as moderate intensity — sufficient to build strength in beginner-to-intermediate lifters.
Goblet squat
Romanian deadlift
Dumbbell walking lunge
Dumbbell shoulder press
High intensity · 80–90% of your 1-rep max. This matches the Lemmey 2009 (80% 1RM, 2x/week, 24 weeks), Flint-Wagner 2009 (90% 1RM, 3x/week, 16 weeks), and Siqueira 2017 (90% 1RM, 3x/week, 16 weeks) protocols from the Ye 2021 meta-analysis. At this intensity, train 2x/week with full recovery between sessions. Always use a spotter or safety equipment.
Barbell back squat
Barbell deadlift
Overhead press
The evidence. The Ye 2022 aerobic meta-analysis (17 RCTs) showed VO2max +2.41 mL/kg/min and HAQ-DI −0.25 (exceeding the MCID of 0.22). The Bilberg 2024 HIIT RCT showed VO2max +3.71 mL/kg/min and waist circumference −2.6 cm. Aerobic exercise improves cardiovascular fitness and function but does NOT significantly reduce DAS28 disease activity — that's resistance training's job. These two modalities are complementary, not interchangeable.
Moderate aerobic training
The Bilberg 2024 protocol. The Bilberg RCT tested HIIT specifically in well-controlled RA. The fitness gains were superior to moderate aerobic training: VO2max +3.71 mL/kg/min and waist circumference −2.6 cm. However, DAS28 did not improve — HIIT is a fitness intervention, not a disease-modifying one. Combine it with resistance training for the full effect.
HIIT protocol
The evidence. The 2025 network meta-analysis of 34 RCTs ranked Pilates highest for pain reduction in RA — above all other exercise modalities. The mechanism is likely a combination of core stabilization (reducing compensatory strain on inflamed joints), mind-body awareness (breaking the pain-tension-guarding cycle), and gentle progressive loading (building strength without high joint forces).
Lateral breathing + pelvic floor
Pelvic tilts + bridge
Single leg stretch + toe taps
Cat-cow + thread the needle
Side-lying leg series
Spine stretch + saw
The evidence. The 2025 network meta-analysis of 34 RCTs ranked Tai Chi highest for DAS28 disease activity reduction in RA. The mechanism is top-down rather than bottom-up: slow, controlled movement with meditative focus reduces sympathetic nervous system tone, lowers cortisol, and quiets NF-κB inflammatory signaling. Resistance training fights inflammation through your muscles. Tai Chi fights it through your nervous system. Together they address both pathways.
I recommend learning Tai Chi from a qualified instructor or following an established video series. Below is a curated beginner Yang-style sequence I recommend for my patients, with key movements explained.
Wuji standing + commencement
Parting the wild horse's mane
Wave hands like clouds
Brush knee and push
Cross hands + closing
The evidence. Fenton 2017 showed that sedentary time increases cardiovascular risk in RA independently of how much formal exercise you do — even if you meet the 150-minute weekly guideline. A 2025 systematic review of 26 studies confirmed exercise snacks improve glucose metabolism, blood pressure, endothelial function, and cerebral blood flow. Your morning workout cannot undo 8 hours of sitting. These can.
Stand and sit × 10
Brisk walk across the room × 3
Bodyweight squats × 10
Staircase climb × 1–2 flights
Your RA exercise prescription
Resistance training 2–3× per week — the disease-modifying backbone. Aerobic or HIIT 2–3× per week — cardiovascular protection. Pilates or Tai Chi 2–3× per week — pain management and neuroendocrine regulation. Exercise snacks every 30 minutes of sitting — vascular, metabolic, and brain health. Three pathways. One prescription.